Lipid Research Special
New specific marker for liposarcoma. Adipophilin/Perilipin 2 is present in milk fat globule membranes and on the surface of lipid droplets in various cultured cell lines; inducible by etomoxir. Detected in the glandular cells of lactating mammary gland, adrenal gland, Sertoli cells, in fat-accumulating hepatocytes of alcoholic cirrhotic fatty liver; In CD68-positive macrophages. Adipocytes are negative.
Synonym PLIN2, ADRP Cat. No. GP40 Suitable for IB, IHC/ paraffin (microwave), frozen sections Species / Reactive with human, bovine, dog, mouse, rat Quantity 100 µL
Polypeptide reacting: MLDP = myocardial lipid droplet protein (also described as OXPAT/PAT-1/Perilipin 5). MLDP pertains to the PAT-family proteins, covering the surface of cytoplasmic lipid droplets and sharing a homologuous domain called PAT. Additional PAT proteins (perilipins 1 - 5) including adipophilin (ADRP/perilipin 2), perilipin (perilipin 1), and TIP47 (perilipin 3) are expressed in differentiation-related stages of lipid metabolism.
Synonym OXPAT, PAT-1, Perilipin 5, LSDP5 Cat. No. GP31 Suitable for IB, IHC/ frozen sections Species / Reactive with human, bovine, mouse, rat Quantity 100 µL
The antiserum reacts specifically with perilipin 1 located at the surface of intracellular storage lipid droplets present e.g. in the adrenal gland, adipocytes of white and brown adipose tissue, Leydig cells.
Cat. No. GP29 Suitable for IB, IHC/ paraffin (microwave), frozen sections Species / Reactive with human, mouse, rat Quantity 100 µL