Hantaviruses are single-stranded enveloped RNA viruses in the Bunyaviridae family, are widespread and are strictly associated with their serotype-specific reservoir hosts. They cause hemorrhagic fever with renal syndrome (HFRS) in Europe and Asia and lead to hantavirus cardiopulmonary syndrome (HCPS) in America. The severity of the disease depends on the infecting virotype with case fatality rates from 0.1% - 10% for HFRS and 25% - 35% for HCPS A. Natural reservoir hosts are rodents, the virus is transmitted to humans via aerosol derived from rodent urine, feces or saliva.
HFRS is caused by Hantaan virus and the closely related Dobrava virus as well as Seoul type and Puumala virus. Hantavirus serotypes show the same geographical distribution pattern as their reservoir hosts. Hantaan virus (host: Apodemus agrarius) is endemic in Asia, Dobrava virus (hosts: different Apodemus sp.) is distributed in the Balkans, Central, Eastern and Southern Europe, the form of the disease ranges from moderate to severe. Puumala serotype (host: Myodes clareolus) is predominant in Scandinavia and Western Europe and causes a mild infection, also called Nephropathia epidemica (NE). In Germany more than 90% of Hantavirus infections are caused by Puumala Virus. People at high risk are farmers, soldiers and campers.
In cases of Hantavirus Infections in Europe
Puumala Virus: IgG & IgM ELISA and IgG/IgM IFT
In cases of Hantavirus infections in Europe and Asia
Dobrava/Hantaan Virus: IgG & IgM ELISA and IgG/IgM IFT
Indirect immunofluorescence test for detection of antibodies against hantavirus Dobrava and Hantaan serotypes in serum. Hantaan and Dobrava Virus are the causative agents for 'Hemorrhagic Fever with Renal Syndrome' (HFRS).
Cat. No. PR77065 Quantity 60 tests
Single-well ELISA for detection of IgG- und IgM-antibodies against hantavirus Dobrava and Hantaan serotypes in human serum. Hantavirus serotypes Dobrava and Hantaan are causative agents of 'Hemorrhagic Fever with Renal Syndrome (HFRS) in Europe and Asia.
Synonym Bunyavirus Cat. No. PR59165 Quantity 96 tests
Indirect immunofluorescence test for detection of antibodies against hantavirus Puumala serotype in serum. Puumala Virus is the causative agent for the milder form of 'Hemorrhagic Fever with Renal Syndrome' (HFRS), and is also called Nephropathia epidemica.
Cat. No. PR77056 Quantity 60 tests
Single-well ELISA for detection of IgG- and IgM-antibodies against hantavirus Puumala serotype in human serum. Hantavirus serotype Puumala is the causative agents of a mild form of 'Hemorrhagic Fever with Renal Syndrome' (HFRS), called Nephropathia epidemica, in Europe.
Synonym Hanta Virus, Bunyavirus, Bunyaviridae Cat. No. PR59156 Quantity 96 tests