Tumor-Associated Antigens
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LK2H10 represents an excellent marker for most neuroendocrine, neuronal and adrenal tumors. Merkel cell tumors of skin and small cell lung CA react weakly. The antibody reacts with the 68 kD protein (chromogranin A).
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| Cat. No. |
10702 |
| Suitable for |
IHC, WB/ paraffin sections, frozen sections |
| Species / Reactive with |
human, monkey, pig, rabbit, rat |
| Quantity |
1 mL |
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Reacts with the 400 kD mucous glycoprotein in the glycocalix of glandular epithelial cells and in carcinoma cells. No cross-reaction with leukemias and no reaction with normal rectal epithelia and colorectal adenomas.
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| Cat. No. |
10824 |
| Suitable for |
ICC, IHC, WB/ paraffin sections, frozen sections |
| Species / Reactive with |
human |
| Quantity |
1 mL |
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Recognizes melanoma-associated antigen in melanoma cells and nevocellular nevi. Cross-reaction with carcinoids; no reaction with normal melanocytes or epithelium except for mast cells, histiocytes, bronchial glands.
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| Cat. No. |
10819 |
| Suitable for |
ELISA, ICC, IHC, WB/ paraffin sections, frozen sections |
| Species / Reactive with |
human |
| Quantity |
1 mL |
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Mucin is an important tumor associated marker for adenocarcinomas. The antibody shows specificity to gastric mucosa, but is also reactive with stomach and colon carcinomas. Most breast carcinomas are negative.
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| Cat. No. |
16075 |
| Suitable for |
IHC, WB/ paraffin sections, frozen sections |
| Species / Reactive with |
human, mammals |
| Quantity |
1 mL |
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BC-2 is reactive with 90% of breast carcinoma, most epithelial ovarian carcinoma and a high proportion of the lung, urogenital and gastrointestinal carcinomas. Recognizes a five aa epitope of the MUC-1 core protein.
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| Cat. No. |
16079 |
| Suitable for |
IHC, WB/ paraffin sections, frozen sections |
| Species / Reactive with |
human |
| Quantity |
1 mL |
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The antibody reacts with mucin from small and large intestine and to a weaker extent with salivary and breast epithelia. Stomach, pancreas, kidney, and ovary epithelia are negative. Positive reaction of gastric and colon carcinoma.
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| Cat. No. |
16074 |
| Suitable for |
IHC, WB/ paraffin sections, frozen sections |
| Species / Reactive with |
human |
| Quantity |
1 mL |
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Reactive with the 185 kD c-erb B2 membrane protein which is overexpressed in carcinomas.
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| Cat. No. |
11418 |
| Suitable for |
ICC, IHC, RIA, WB/ paraffin sections, frozen sections |
| Species / Reactive with |
human |
| Quantity |
1 mL |
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Positive identification of primary and metastatic prostatic carcinoma. The antibody is highly specific for benign and malignant metastatic prostate cancer.
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| Synonym |
PSA |
| Cat. No. |
10815 |
| Suitable for |
IHC, WB/ paraffin sections, frozen sections |
| Species / Reactive with |
human |
| Quantity |
1 mL |
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Recognizes benign and malignant prostatic epithelium. Occasionally, some pancreatic islet cells, carcinomas of the bladder, and carcinoids are also stained.
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| Synonym |
PAP |
| Cat. No. |
10816 |
| Suitable for |
IHC, WB/ paraffin sections, frozen sections |
| Species / Reactive with |
human |
| Quantity |
1 mL |
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SY38 stains neuronal and adrenal tumors such as pheochromocytomas, paragangliomas, neuroblastomas and neuroendocrine tumors of epithelial origin, e.g. pancreatic islet cell carcinoma, brochial and gastrointestinal carcinoids.
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| Cat. No. |
65012 |
| Suitable for |
ICC, IHC, WB/ paraffin sections, frozen sections |
| Species / Reactive with |
human, bovine, mouse, rat |
| Quantity |
5 mL |
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