Structural Proteins

Reacts specifically with actin in Immunoblotting and ELISA. It is intended for use in immunostaining of cell suspensions and acetone-fixed frozen tissue sections.

Specific for skeletal and non-muscle actin isoforms (Mr 43,000). The antibody also detects nuclear actin isoforms. Epitope location: NVPAMYVAVLDSGVTHNVPIYHAIMRLDLA.

ASM-1 represents an excellent marker for myogenic soft tissue tumors and smooth muscle differentiation. Stains leiomyosarkoma, leiomyoma, certain stromal cells surrounding infiltrating ductal carcinoma of breast.

ASM-1 represents an excellent marker for myogenic soft tissue tumors and smooth muscle differentiation. Stains leiomyosarkoma, leiomyoma, certain stromal cells surrounding infiltrating ductal carcinoma of breast.

Marker for the discrimination of cardiac (fetal) alpha-actin from other actin isoforms present in skeletal and smooth muscle. Fetal actin can be localized in regenerating muscle after injury (satellite cells).

Marker for the discrimination of cardiac (fetal) alpha-actin from other actin isoforms present in skeletal and smooth muscle. Fetal actin can be localized in regenerating muscle after injury (satellite cells).

Drebrin has originally been described only in neuronal cells, but has been recently found also in the actin-rich lamellipodia and filopodia of motile cells. It is enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells. Negative: hepatocytes and cross-striated muscle.

Specific for drebrin, a widespread actin-associating protein of 70 kD (SDS-PAGE mobility shows Mr 120,000), enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells. Positive staining was found in many tissues. Especially prominent in the mesangial cells of renal glomeruli and in the Sertoli cells of testis. Negative: hepatocytes and cross-striated muscle.

Specific for drebrin isoforms E2 and A, widespread actin-associating proteins of 70 kD (SDS-PAGE mobility shows Mr 120,000). Drebrin has originally been described only in neuronal cells, but has been found also in the actin-rich lamellipodia and filopodia of motile cells. It is enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells. Negative: hepatocytes, cross-striated muscle.