Cell Surface Marker / CD
Marker for alterations of the alpha-6 integrin transmembrane proteins during tumor progression. Directed against the CD49f antigen (VLA-6 alpha chain).
Synonym CD49F Cat. No. 10709 Suitable for Flow Cytometry, ICC, IHC, WB/ frozen sections Species / Reactive with human Quantity 1 mL
The c-Kit proto-oncogene encodes a transmembrane receptor with tyrosine kinase activity and is closely related to the platelet-derived growth factor receptor family. Expressed in normal breast epithelium, melanocytes, mast cells, glial cells. In neoplasms the antigen is expressed in SLCC, breast carcinomas, glioblastomas, melanomas and acute/chronic myelogenous leukemias during myeloid blast crisis. Potential marker for telocytes (also described as ICLC, i.e. interstitial Cajal-like cells)
Synonym C-Kit Cat. No. 16105 Suitable for IHC Species / Reactive with human Quantity 1 mL
CD34 is a single chain transmembrane glycoprotein (105-120 kD) selectively expressed on human lymphoid, myeloid haematopoietic progenitor cells and on vascular endothelium. Useful for studying benign and malignant vascular tumors and for characterizing leukemias. Potential marker for telocytes in various tissues.
Cat. No. 16109 Suitable for IHC Species / Reactive with human Quantity 1 mL
CD44, a transmembrane protein expressed by lymphocytes and several normal epithelial cells, is involved in T-lymphocyte activation, lymphocyte homing, interaction with hyaluronic acid and may act as an adhesion molecule.
Synonym CD44 Cat. No. 16080 Suitable for ICC, IHC, WB/ paraffin (microwave), frozen sections Species / Reactive with human Quantity 1 mL
The antibody reacts with the cellular adhesion molecule ICAM-3/CD50, a single chain polypeptide. It is glycosylated and resistant to treatment with phosphatidylinositol phospholipase C, and probably not PI-anchored to the membrane.
Synonym CD50 Cat. No. 16096 Suitable for ICC, IHC, WB/ paraffin (microwave), frozen sections Species / Reactive with human Quantity 1 mL