Apoptosis / Cellular Degradation
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Useful for research in ubiquitin-associated degradation and autophagy and for detection of neurofibrillary tangles in the brain of Alzheimer disease patients, in Parkinson diseases and various chronic liver diseases. Human p62 protein, present in intracytoplasmic inclusions is found in many tissues and cells, serving probably a common cellular signal transduction mechanism.
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| Synonym |
sequestosome 1, SQSTM1, ubiquitin-binding protein |
| Cat. No. |
GP62-C |
| Suitable for |
IHC, WB/ paraffin (microwave), frozen sections |
| Species / Reactive with |
human, mouse, rat |
| Quantity |
100 µL |
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Human p62 protein, present in intracytoplasmic inclusions is found in many tissues and cells, serving probably a common cellular signal transduction mechanism.
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| Synonym |
sequestosome 1, SQSTM1 |
| Cat. No. |
GP62-N |
| Suitable for |
IHC, WB/ paraffin (microwave), frozen sections |
| Species / Reactive with |
human, rat |
| Quantity |
100 µL |
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p97 ATPase (VCP) is implicated in homotypic membrane fusion events and is related to the N-ethyl maleimide-sensitive fusion protein NSF/Sec18p. The antibody reacts with p97 subunit of 15S Mg2+-ATPase
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| Synonym |
VCP, valosin-containing protein |
| Cat. No. |
65178 |
| Suitable for |
WB |
| Species / Reactive with |
human, rabbit, rat, xenopus (not with budding yeast Cdc48p) |
| Quantity |
5 mL |
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p97 ATPase (VCP) is implicated in homotypic membrane fusion events and is related to the N-ethyl maleimide-sensitive fusion protein NSF/Sec18p. The antibody reacts with p97 subunit of 15S Mg2+-ATPase
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| Synonym |
VCP, valosin-containing protein |
| Cat. No. |
61078 |
| Suitable for |
WB |
| Species / Reactive with |
human, rabbit, rat, xenopus (not with budding yeast Cdc48p) |
| Quantity |
50 µg |
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p97 ATPase (VCP) s implicated in homotypic membrane fusion events and is related to the N-ethyl maleimide-sensitive fusion protein NSF/Sec18p. The antibody reacts with p97 subunit of 15S Mg2+-ATPase
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| Synonym |
VCP, valosin-containing protein |
| Cat. No. |
65278 |
| Suitable for |
WB |
| Species / Reactive with |
human, rabbit, rat, xenopus (not with budding yeast Cdc48p) |
| Quantity |
500 µL |
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Recognizes the p27 subunit of the 20S subcomplex within the 26S hetero-oligomeric protein complex and the free cytosolic form of 20S cylinder particles.
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| Cat. No. |
61244 |
| Suitable for |
Affinity Chromatography, IF, IHC, WB/ frozen sections |
| Species / Reactive with |
human, rat, Xenopus laevis |
| Quantity |
250 µL |
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Recognizes the p27 subunit of the 20S subcomplex within the 26S hetero-oligomeric protein complex and the free cytosolic form of 20S cylinder particles.
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| Cat. No. |
65144 |
| Suitable for |
ICC, IHC, WB/ frozen sections |
| Species / Reactive with |
human, rat, Xenopus laevis |
| Quantity |
5 mL |
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Recognizes the p32 subunit of the 20S subcomplex within the 26S hetero-oligomeric protein complex and the free cytosolic form of 20S cylinder particles.
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| Cat. No. |
65145 |
| Suitable for |
ICC, IHC, WB/ frozen sections |
| Species / Reactive with |
human, Xenopus laevis |
| Quantity |
5 mL |
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The p52 subunit (Mr 52,000) is the major antigen of the 19S cap complex, which is a subcomplex of the 26S proteasome, implicated in ATP- and ubiquitin-dependent protein degradation.
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| Cat. No. |
65179 |
| Suitable for |
WB |
| Species / Reactive with |
human, rat, xenopus (rat cell lines) |
| Quantity |
5 mL |
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