anti-AAV-8 (intact particle)  mouse monoclonal, ADK8

For characterization of different stages of infection and very useful for analysis of the AAV assembly process. ADK8 specifically reacts with intact adeno-associated virus particles, empty and full capsids. Recognizes a conformational epitope of assembled capsids. Not for use in immunoblotting.
Cat. No. 651160
Synonyms Adeno-associated virus 8; AAV8
Suitable for Dot Blots, ELISA, IF, IHC, IP, Neutralisation Assay / frozen sections
Isotype IgG2a kappa
Presentation supernatant
Clone ADK8
Host mouse
Antibody Type monoclonal
Dilution prediluted for IHC, IF
Species / Reactive with AAV-8, monkey
Quantity 5 mL
Delivery time 3 working days within Germany

Get Acrobat Reader


Kuck D, Kern A, Kleinschmidt JA (2007). Development of AAV serotype-specific ELISAs using novel monoclonal antibodies. J Virol Methods 140, 17-24

Sonntag F, Köther K, Schmidt K, Weghofer M, Raupp C, Nieto K, Kuck A, Gerlach B, Böttcher B, Müller OJ, Lux K, Hörer M, Kleinschmidt JA: The assembly-activating protein promotes capsid assembly of different adeno-associated virus serotypes. J Virology 85, 12686-12697 (2011)

Gurda BL, Raupp C, Popa-Wagner R, Naumer M, Olson NH, Ng R, McKenna R, Baker TS, Kleinschmidt JA, Agbandje-McKenna M: Mapping a neutralizing epitope onto the capsid of adeno-associated virus serotype 8. J Virology 86, 7739-7751 (2012)

Raupp C, Naumer M, Müller OJ, Gurda BL, Agbandje-McKenna M, Kleinschmidt JA: The threefold protrusions of adeno-associated virus type 8 are involved in cell surface targeting as well as postattachment processing. J Virol 17, 9396-9408 (2012); doi:10.1128/JVI.00209-12

Mietzsch M, Grasse S, Zurawski C, Weger S, Bennett A, Agbandje-McKenna M, Muzyczka N, Zolotukhin S, Heilbronn R: OneBac: Platform for scalable and high-titer production of adeno-associated virus serotype 1-12 vectors for gene therapy. Hum Gene Ther 25, 212-222 (2014); doi: 10.1089/hum.2013.184